Isopropyl myristate, present at 100 mgl, reached 94% of its chemical oxygen demand in 28 days using a municipal waste water inoculum in the closed bottle test4. Viscous products, such as creams and ointments, can be difficult to filter and are normally diluted in a sterile solvent, such as isopropyl myristate ipm. Role of isopropyl myristate, isopropyl alcohol and a combination of both in hydrocortisone permeation across the human stratum corneum. It is generally safe, although some people with skin conditions may wish to avoid products containing. Low viscosity fluid nongreasy emollient, tolerates wide ph range, compatible with most surfactants.
Methyl tetradecanoate, myristic acid methyl ester cas number 124107. Material safety data sheet duke safety office duke university. Isopropyl myristate, nf 110270 is145 spectrum chemical. Isopropyl myristate msds material safety data sheet or sds, coa and coq, dossiers, brochures and other available documents. It is also used as a pesticide against head lice which works. Isopropyl myristate standard liquid parameters specification test methods identification passes test uspnf appearance passes test inhouse method odor passes test inhouse method acid value, mgkohg 1. Firstaid measures general advice if symptoms persist, call a physician. Safety data sheet northwest missouri state university. Its also perfect as a perfume diluent in place of other oils or alcohol. Sample recipe for isopropyl myristate making cosmetics. Pediculicide widespread and common in children between the ages of 3 and 12. These products will have been purified before being used in the cosmetics to remove any residual isopropyl alcohol.
Spectrum chemical nf products are manufactured, packaged and stored under current good manufacturing practices cgmp per 21cfr part 211 in fda registered and inspected facilities. Keep containers tightly closed in a dry, cool and wellventilated place. Other local effects have included nasal and lung irritation during inhalation of aerosols in monkeys and rats, acne development after application to rabbit skin, and increased permeability of human. Isopropyl myristate is defined as a synthetic oil that is popularly used in both the cosmetics industry as well as the pharmaceutical industry. Ester of isopropyl alcohol and myristic acid vegetablederived.
Apr 27, 2020 isopropyl myristate msds pdf material safety data sheet. Identification of the substancemixture and of the companyundertaking 1. In cosmetics and personal care products, isopropyl myristate functions as a binder, and skinconditioning agent a emollient. Isopropyl myristate is also a great, nontoxic solvent for monster clay. Collect and dispose of spillage as indicated in section of the sds. Isopropyl myristate, the ester of myristic acid and isopropyl alcohol, is also used in topical medications. Cetearyl ethylhexanoate and isopropyl myristate shopify. Isopropyl myristate consists of esters of isopropyl alcohol and saturated high molecular weight fatty acids, principally myristic acid. Isopropyl myristate msds material safety data sheet isopropyl myristate 1.
Tetradecanoic acid, 1methylethyl ester chemical formula. Isopropyl myristate cas 110270 822102 emd millipore. Isopropyl myristate 98% isopropyl myristate, 98% min. Isopropyl myristate msds pdf material safety data sheet. Mar 21, 2020 isopropyl myristate msds pdf material safety data sheet. Committee to evaluate drugs ced isopropyl myristate. Isopropyl myristate name isopropyl myristate product identification naturalidentical flavouring substance chemical name isopropyl tetradecanoate chemical formulae c17h34o2 cas number 110270 fema number 3556 einecs number 2037514 physicochemical properties aspect colourless liquid organoleptic description.
Isomyst, stepan d50, bisomel, ipm, tegester, crodamol i. It has been attacked by scaremongers either from ignorance or more likely from a cynical desire to sell inferior products at high prices. Isopropyl myristate in mumbai, maharashtra get latest price. Isopropyl myristate can be used to dilute aroma chemicals. Import data and price of isopropyl myristate under hs code. Ipm is used to dissolve lanolin and other oils, and is commonly used as a degreasant or softener in sunscreens, face creams and lipsticks. Isopropyl myristate safety data sheet according to federal register vol.
Therefore, isopropyl myristate is used as a solubilizing, spreading, and penetrat. Isopropyl myristate ipm makeup and adhesive remover. Role of isopropyl myristate, isopropyl alcohol and a. This structure is also available as a 2d mol file or as a computed 3d sd file the 3d structure may be viewed using. Isopropyl myristate is a light, colorless, oily liquid. Show this safety data sheet to the doctor in attendance. Steritest ez system sterility testing of products to be. Lastly, isopropyl myristate is also believed to have strong skin penetrating properties. Safety data sheet according to federal register vol. Isopropyl myristate ipm has produced slight irritation of human skin, mild irritation of the rabbit eye and moderate irritation of rabbit skin. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Packaging and storage preserve in tight, lightresistant containers. Isopropyl myristate is a synthetic oil widely used in the cos.
Green synthesis of isopropyl myristate in novel single phase. Find out more about isopropyl myristate, all the commercially available products, formulation examples and other related technical info. Isopropyl myristate is perfectly safe as a cosmetic ingredient and there are no issues with it as far as end users are concerned. Pdf enzymatic synthesis of isopropyl myristate using. Wear protective clothing as described in section 8 of this safety data sheet. Can a product be alcohol free while containing isopropyl. Isopropyl myristate is a polar emollient and is used in cosmetic and topical medicinal preparations where good absorption into the skin is desired. Gentle oilbased makeup remover which removes many types of makeup including pax prosaide and grease makeups. Its used in cosmetic and topical medicinal preparations. Committee to evaluate drugs ced recommendations and reasons this document posted april 2010 isopropyl myristate product. Isopropyl myristate finds many applications in food, cosmetic and pharmaceutical industries as an emollient, thickening agent, or lubricant. Isopropyl myristate resultz 50% topical solution class of drugs. Using a homogeneous reaction phase, nonspecific lipase derived from candida antartica, marketed as novozym 435, was determined to be most suitable for the enzymatic synthesis of isopropyl myristate.
Isopropyl myristate is being studied as a skin enhancer. Isopropyl myristate, with the chemical formula ch 3 ch 2 12 cooch ch 3 2, is an ester of myristic acid, an essential fatty acid derived from palm kernel oil and isopropyl alcohol. Used as an emollient and lubricant in preshaves, aftershaves, shampoos, bath oils. Isopropyl myristate ipm is the ester of isopropyl alcohol and myristic acid. Isopropyl myristate revision date 24jan2018 component casno weight % isopropyl myristate 110270 95 4. Isopropyl myristate is the ester of isopropyl alcohol and myristic acid. Chemical product and company identification product name. Hallstar ipmnf is a multifunctional emollient, solvent, spreading agent, penetrant synthetically produced ester of vegetal myristic acid and petrochemical isopropyl alcohol that conforms to the requirements of the national formulary monograph for isopropyl myristate. Steritest ez system sterility testing of products to be diluted in isopropyl myristate filtration is the pharmacopoeia method of choice for sterility testing. Effectiveness of isopropyl myristatecyclomethicone d5. This is a valuable attribute, as isopropyl myristate can help other skin healing chemicals to penetrate more deeply.
Sigmaaldrich offers a number of isopropyl myristate products. It was also used as oilwatertype tacrolimus fk506 solvent. Apr 19, 2017 isopropyl myristate is defined as a synthetic oil that is popularly used in both the cosmetics industry as well as the pharmaceutical industry. Isopropyl myristate 110270 1 225 version 2 revision date 07112008 print date 07112008 page 4 8 requirements for storage areas and containers. Isopropyl myristate was used as oil phase in the preparation of formulations. Final report on the safety assessment of myristyl myristate. Pdf isopropyl myristate production process optimization. View detailed import data, price, monthly trends, major importing countries, major ports of isopropyl myristate under hs code 2915.
Despite its popularity with manufacturers, some side effects have been reported. Sds safety data sheet isopropyl alcohol, 99% azer scientific inc 701 hemlock road morgantown pa 19543 610. Long chain fatty acid esters, structurally similar to isopropyl myristate, were rapidly degraded by mixed sewage sludge1,2,3. Isopropyl myristate is a synthetic oil used as an emollient, thickening agent, or lubricant in beauty products. This sds is intended to provide a brief summary of our knowledge and guidance. Isopropyl myristate 98% isopropyl tetradecanoate sigmaaldrich. Isopropyl myristate is found in several everyday beauty products and is generally considered safe for consumer use.
It is widely used as a nontoxic alternative for the control of head lice, as an emollient, and a lubricant. Myristic acid isopropyl ester isopropyl tetradecanoate 1. Any website that suggests this material is harmful should be ignored. Material safety data sheet section 1 isopropyl myristate 1 chemical product and company identification msds name. Enzymatic synthesis of isopropyl myristate using immobilized lipase from bacillus cereus mtcc 8372 article pdf available in acta microbiologica et immunologica hungarica 553. The substance identity section is calculated from substance identification information from all echa databases.
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